Peptide Database

Peptide NameHRA3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC158H277N47O53

DescriptionStandard

        LESEVTAIKNALKKTNEAVSTLGNGVRVLATAVRE
    

Molecular Weight3683.17 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0221

GRAVY Index-0.02

Hydrophobic Moment 0.72

Boman Index-0.01

Instability Index2.43

Aliphatic Index 111.43

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1654.43

LogP -19.74

H-bond Donors 58.0

H-bond Acceptors 54.0

Rotatable Bonds 128.0

Heavy Atoms 258.0

Ring Count 0.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326434 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHuman Metapneumovirus(hMPV):inhibition of viral infection in LLC-MK2 cells

Activity3.24 μM

MethodIC50

RECORD: Rec_0407433 VERIFIED: YES