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MYP_086344
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Basic Information
LP1A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
21 amino acids
C116H187N35O29
Standard
Sequence
QRFSQPTFKLPQGRLTLSRKF
Physicochemical Analysis
2535.94 Da
12.00
4.76
4.55
0.2266
-0.89
0.54
-0.29
50.06
55.71
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1075.67
-10.80
38.0
34.0
84.0
180.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0209093 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae 13883
25 μg/mL
MIC
PMID20096726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20096726/
RECORD: Rec_0239173 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
N-terminus is a pyroglutamate (XXQ). LP2A and LP3A were also detected but showed no or poor activity (MIC 200 uM)
Bio-Activity Profile
Antimicrobial
LP2A and LP3A were also detected but showed no or poor activity
200 μM
MIC
PaperFunctional analysis of four processing products from multiple precursors encoded by a lebocin-related gene from Manduca sexta
RECORD: Rec_0281468 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus MRSA 43
PMID20096726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20096726/
RECORD: Rec_0293667 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 19.0%, T 23.8%, C 57.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0314038 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli O157:H7 25922
25 μg/mL
MIC
PMID20096726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20096726/
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