Peptide Database

Peptide NameAlpha-insect toxin LqhaIT

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC329H490N94O94S8

DescriptionStandard

        VRDAYIAKNYNCVYECFRDAYCNELCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRVPGKCHRK
    

Molecular Weight7522.50 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.34

Charge Density (pH 7.0) 0.0566

GRAVY Index-0.51

Hydrophobic Moment 0.63

Boman Index-0.07

Instability Index33.47

Aliphatic Index 51.82

Aromaticity 0.1515

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3056.84

LogP -31.00

H-bond Donors 114.0

H-bond Acceptors 107.0

Rotatable Bonds 236.0

Heavy Atoms 525.0

Ring Count 16.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243535 VERIFIED: YES

Provenance & Taxonomy

OrganismLeiurus quinquestriatus hebraeus [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense