Peptide Database

Peptide NameDermaseptin-B8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC367H596N96O123S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRENEDEEEQEDDEQSEMKRGLWSKIKEAGKAALTAAGKAALGAVSDAVGEQ
    

Molecular Weight8417.42 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-7.48

Net Charge (pH 7.4) -7.74

Charge Density (pH 7.0) -0.0971

GRAVY Index-0.34

Hydrophobic Moment 0.55

Boman Index-0.03

Instability Index53.37

Aliphatic Index 88.83

Aromaticity 0.0519

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3570.74

LogP -34.00

H-bond Donors 122.0

H-bond Acceptors 119.0

Rotatable Bonds 301.0

Heavy Atoms 589.0

Ring Count 5.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103737 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence