MYP_086262
Esculentin-1
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Insecticidal/Pest control
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Insecticidal activity
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytolysis / cell lysis
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Cytolytic activity
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Standard
46 amino acids
C215H378N62O60S3
Standard
GIFSKLGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
4887.88 Da
9.83
5.74
5.49
0.1248
0.08
0.61
0.03
-6.30
112.17
0.0217
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
2000.85
-18.42
72.0
69.0
179.0
340.0
1.0
47.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0003022
VERIFIED: YES
Provenance & Taxonomy
Pelophylax lessonae [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Anti-Gram-negative
Anti-Gram-positive
Cytolytic
Hemolytic
Gram-negative and Gram-positive bacteria
RECORD: Rec_0009623
VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Antifungal
Candida albicans
0.5 μM
MIC
RECORD: Rec_0012708
VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
E.coliD21
0.2 μM
MIC
RECORD: Rec_0015903
VERIFIED: YES
Provenance & Taxonomy
Edible frog [Animal]
Esculentin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0025667
VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial
Antifungal
Insecticidal
Escherichia coli D 21(lethal concentration LC 0.2 uM), Bacillus megaterium BmII (LC 0.1 uM), Staphylococcus aureus Cowan 1(LC 0.4 uM), Pseudomonas aeruginosa ATCC 15692 (LC 0.7 uM), Candida albicans (LC 0.5 uM)
Showing 5 records on this page · Page 1 of 5