Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC373H565N93O99S9

DescriptionStandard

        MKIFYYFLHFLCYVTFILPATCTLVDPNRCSQNFGYCRRRCFKYEKQIDICLSPSKICCIERLFEEDS
    

Molecular Weight8224.62 Da

Isoelectric Point (pI)8.13

Net Charge (pH 7.0)1.51

Net Charge (pH 7.4) 1.11

Charge Density (pH 7.0) 0.0223

GRAVY Index0.07

Hydrophobic Moment 0.61

Boman Index0.03

Instability Index69.51

Aliphatic Index 78.82

Aromaticity 0.1765

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3105.13

LogP -21.38

H-bond Donors 117.0

H-bond Acceptors 111.0

Rotatable Bonds 266.0

Heavy Atoms 574.0

Ring Count 16.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034324 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0052195 VERIFIED: NO