Peptide Database

Peptide NameLEAP-2

Function Ontology

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Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC185H299N59O59S5

DescriptionStandard

        MTPFWRGVTRPVGASCRDDSECFSRLCRSKRCSVTISEE
    

Molecular Weight4454.04 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)1.48

Net Charge (pH 7.4) 1.19

Charge Density (pH 7.0) 0.0378

GRAVY Index-0.51

Hydrophobic Moment 0.72

Boman Index-0.24

Instability Index80.30

Aliphatic Index 44.87

Aromaticity 0.0769

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1933.32

LogP -24.79

H-bond Donors 76.0

H-bond Acceptors 66.0

Rotatable Bonds 145.0

Heavy Atoms 308.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255708 VERIFIED: YES

Provenance & Taxonomy

OrganismGekko japonicus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)