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MYP_086223
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Basic Information
KF-8
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Standard
8 amino acids
C42H63N15O14
Standard
Sequence
KHNRGDEF
Physicochemical Analysis
1002.04 Da
6.75
-0.15
-0.41
-0.0187
-2.46
0.26
-0.65
27.74
0.00
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
501.31
-5.76
17.0
15.0
34.0
71.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0318569 VERIFIED: NO
Provenance & Taxonomy
Oryza sativa [Plant]
Octapeptide
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Antioxidant Neuroprotective Vasoprotective Anti-apoptotic
NIH/3T3 cells (In vitro)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Histology; Apoptosis assay; Enzyme activity assay
PaperPatent 3, 294, 284, 729, 276, 940 Patent3, 294, 284, 729, 276, 940
RECORD: Rec_0356727 VERIFIED: NO
Provenance & Taxonomy
Oryza sativa [Plant]
Octapeptide
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Antioxidant Neuroprotective Vasoprotective Anti-apoptotic
Human umbilical vein endothelial cells (HUVECs) (In vitro)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Histology; Apoptosis assay; Enzyme activity assay
PaperPatent 3, 294, 284, 729, 276, 940 Patent3, 294, 284, 729, 276, 940
RECORD: Rec_0367038 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperZhang J., Zhang H., Wang L., Guo H., Wang X., Yao H.. Antioxidant activities of the rice endosperm protein hydrolysate: identification of the active peptide. Eur. Food Res. Technol., 229 (2009), 709-719.
RECORD: Rec_0393510 VERIFIED: NO
Provenance & Taxonomy
Oryza sativa [Plant]
Octapeptide
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Antioxidant Neuroprotective Vasoprotective Anti-apoptotic
Mice (In vivo)
Cell viability assay; Cytotoxicity assay; ELISA; Western blot; Histology; Apoptosis assay; Enzyme activity assay
PaperPatent 3, 294, 284, 729, 276, 940 Patent3, 294, 284, 729, 276, 940
RECORD: Rec_0401649 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant