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MYP_086123
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Basic Information
Lantibiotic streptin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
46 amino acids
C231H367N59O70S4
Standard
Sequence
MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
Physicochemical Analysis
5219.00 Da
8.93
2.47
2.19
0.0536
-0.39
0.46
-0.05
21.45
63.48
0.1087
8480.00
8605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2110.28
-22.05
77.0
77.0
170.0
364.0
8.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005566 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID12732544 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12732544/; https://www.uniprot.org/uniprotkb/P0C0H8/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0054709 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A4Q1Q3F4/entry
RECORD: Rec_0074368 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes serotype M28 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID16088825 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16088825/; https://www.uniprot.org/uniprotkb/Q48TR2/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0162069 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
RECORD: Rec_0291258 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes serotype M2 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID16636287 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16636287/; https://www.uniprot.org/uniprotkb/Q1JH10/entry; https://bblserver.org.in/ampdb/
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