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MYP_086098
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Basic Information
rabbit NP-5 defesin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
33 amino acids
C143H237N51O43S6
Standard
Sequence
VFCTCRGFLCGSGERASGSCTINGVRHTLCCRR
Physicochemical Analysis
3551.12 Da
9.01
3.76
3.41
0.1141
0.11
0.38
-0.07
50.83
56.06
0.0606
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1534.47
-22.26
64.0
54.0
116.0
243.0
3.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051796 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSelsted M. E., Brown D. M, DeLange R. J., Harwig S. S., Lehrer R. I.. Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J. Biol. Chem., 260, 4579-4584, 1985.
RECORD: Rec_0066084 VERIFIED: NO
Provenance & Taxonomy
Mammalia [Animal]
40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0175825 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0214869 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus strains 566, 502A, J.F. (reduction 0.1-0.4 logs), Staphylococcus epidermidis UCLA-622 (reduction 0.4 logs), S. pneumoniae Type III (reduction 1.9 log), S. agalactiae Type I-A
PaperPrimary structures of six antimicrobial peptides of rabbit peritoneal neutrophils
RECORD: Rec_0236392 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperNeutrophil antibiotic peptide NP-5 Evidence URLhttps://www.uniprot.org/uniprotkb/P07466/entry
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