Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC372H593N105O101S9

DescriptionStandard

        MRFAVLLFTMFFFMSQVLPVRGKFKEICERPNGSCRDFCIETEIHVGRCLNSRPCCLPLGNQPRIESTTPKKD
    

Molecular Weight8440.92 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.17

Charge Density (pH 7.0) 0.0485

GRAVY Index-0.13

Hydrophobic Moment 0.45

Boman Index-0.04

Instability Index56.05

Aliphatic Index 70.68

Aromaticity 0.0959

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3310.23

LogP -30.24

H-bond Donors 120.0

H-bond Acceptors 115.0

Rotatable Bonds 277.0

Heavy Atoms 587.0

Ring Count 14.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249437 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence