Peptide Database

Peptide NamePeptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC957H1478N284O272S13

DescriptionStandard

        MSRRSMLLAWALPSLLRLGAAQETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRSP
    

Molecular Weight21730.56 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)5.23

Net Charge (pH 7.4) 4.42

Charge Density (pH 7.0) 0.0267

GRAVY Index-0.26

Hydrophobic Moment 0.77

Boman Index0.04

Instability Index59.51

Aliphatic Index 79.18

Aromaticity 0.0867

Extinction Coeff. Reduced 44920.00

Extinction Coeff. Oxidized 45295.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8853.37

LogP -108.70

H-bond Donors 313.0

H-bond Acceptors 299.0

Rotatable Bonds 692.0

Heavy Atoms 1526.0

Ring Count 44.0

Amide Bonds 217.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337421 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Chemotactic Cytotoxic Non-hemolytic

TargetGram Positive Bacteria