Peptide Database

Peptide NameDEFA4 isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC266H431N73O89

DescriptionStandard

        IRSLALLGAILLVALQARAEPLQAIADEATAQEQPGADDQEVVDSFAWDERATLQVS
    

Molecular Weight6075.70 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.22

Net Charge (pH 7.4) -7.43

Charge Density (pH 7.0) -0.1267

GRAVY Index0.12

Hydrophobic Moment 0.43

Boman Index0.11

Instability Index48.43

Aliphatic Index 116.67

Aromaticity 0.0351

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2609.52

LogP -26.02

H-bond Donors 87.0

H-bond Acceptors 82.0

Rotatable Bonds 201.0

Heavy Atoms 428.0

Ring Count 5.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037001 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Defensin Non-hemolytic Non-ribosomal