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MYP_086046
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Basic Information
Temporin-CPa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C76H123N15O16
Standard
Sequence
IPPFIKKVLTTVF
Physicochemical Analysis
1502.88 Da
10.00
1.76
1.55
0.1352
1.11
0.56
0.42
23.58
134.62
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
487.44
0.18
16.0
18.0
45.0
107.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251191 VERIFIED: YES
Provenance & Taxonomy
Rana capito [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. glabrata ATCC 2001
12.5 μM
MIC
PMID19635516;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19635516/
RECORD: Rec_0253852 VERIFIED: YES
Provenance & Taxonomy
Lithobates capito [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
G. Glabrata
12.5 μM
MIC
PaperAntimicrobial peptides from the skin secretions of the New World frogs Lithobates capito and Lithobates warszewitschii (Ranidae).
RECORD: Rec_0277917 VERIFIED: YES
Provenance & Taxonomy
Lithobates capito [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 90028
25 μM
MIC
PMID19635516 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19635516/
RECORD: Rec_0281524 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 30.8%, E 0.0%, T 30.8%, C 38.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0292580 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
220 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/19635516/ PMID19635516 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19635516/
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