‹ ›
MYP_086046
← PREVIOUS NEXT → BACK
Basic Information
Temporin-CPa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C76H123N15O16
Standard
Sequence
IPPFIKKVLTTVF
Physicochemical Analysis
1502.88 Da
10.00
1.76
1.55
0.1352
1.11
0.56
0.42
23.58
134.62
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
487.44
0.18
16.0
18.0
45.0
107.0
4.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0138935 VERIFIED: YES
Provenance & Taxonomy
Lithobates capito [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. tropicalis
3.1-6.2 μM
MIC
PaperAntimicrobial peptides from the skin secretions of the New World frogs Lithobates capito and Lithobates warszewitschii (Ranidae).
RECORD: Rec_0139133 VERIFIED: YES
Provenance & Taxonomy
Lithobates capito [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus epidermidis
12.5 μM
MIC
PaperAntimicrobial peptides from the skin secretions of the New World frogs Lithobates capito and Lithobates warszewitschii (Ranidae).
RECORD: Rec_0147108 VERIFIED: YES
Provenance & Taxonomy
Rana capito [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBCs
100 μM
Hemolysis
PMID19635516;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19635516/
RECORD: Rec_0149185 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0149725 VERIFIED: YES
Provenance & Taxonomy
Lithobates capito [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
220.0 μM
HC50
PaperJ.M. Conlon et al. / Peptides 30 (2009) 1775-1781. Antimicrobial peptides from the skin secretions of the New World frogs Lithobates capito and Lithobates warszewitschii (Ranidae)
FIRST PREV 1 2 3 4 ... 7 NEXT LAST
Showing 5 records on this page · Page 2 of 7