Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC315H512N82O98S8

DescriptionStandard

        MFQEVKEVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVPVKPKLTDTNTSLESTSAV
    

Molecular Weight7272.45 Da

Isoelectric Point (pI)8.56

Net Charge (pH 7.0)2.45

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0382

GRAVY Index-0.44

Hydrophobic Moment 0.68

Boman Index-0.11

Instability Index22.47

Aliphatic Index 59.22

Aromaticity 0.0781

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2932.05

LogP -29.97

H-bond Donors 109.0

H-bond Acceptors 109.0

Rotatable Bonds 244.0

Heavy Atoms 503.0

Ring Count 9.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192897 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function