Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC443H698N120O109S11

DescriptionStandard

        LRSLPSKMAPCRKMFYFVIALFFVLAQFPSGCRAGLDYYKSLPGGEFAVCETCRLGRGKCRKICLEGEKIYGNCRLNFFCCRPKIL
    

Molecular Weight9801.73 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)9.67

Net Charge (pH 7.4) 9.31

Charge Density (pH 7.0) 0.1125

GRAVY Index0.17

Hydrophobic Moment 0.66

Boman Index0.04

Instability Index40.57

Aliphatic Index 79.42

Aromaticity 0.1395

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3668.05

LogP -27.18

H-bond Donors 139.0

H-bond Acceptors 130.0

Rotatable Bonds 322.0

Heavy Atoms 683.0

Ring Count 17.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036733 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0166285 VERIFIED: NO