Peptide Database

Peptide NameBrevinin-1CG5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC357H586N92O103S6

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDDDEMDVEVEKRFLPMLAGLAANFLPKIVCKITKKC
    

Molecular Weight8007.42 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0219

GRAVY Index-0.04

Hydrophobic Moment 0.68

Boman Index-0.02

Instability Index35.86

Aliphatic Index 103.19

Aromaticity 0.0725

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3175.39

LogP -22.57

H-bond Donors 111.0

H-bond Acceptors 108.0

Rotatable Bonds 280.0

Heavy Atoms 558.0

Ring Count 7.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312560 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops chunganensis [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Cytolytic Hemolytic Non-ribosomal

TargetCandida albicans

MethodQualitative functional evidence