Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC475H773N121O135S9

DescriptionStandard

        MKLFLVLTILLFEVPKDTARPRKCFSNITGYCRKKCQMGEIFETGCVNGKLCCVNEGENKKYLKPEKLPVSSVKSNENKDYIILPTMTIFTVE
    

Molecular Weight10627.53 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)4.46

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.0479

GRAVY Index-0.16

Hydrophobic Moment 0.59

Boman Index-0.01

Instability Index23.39

Aliphatic Index 85.81

Aromaticity 0.0860

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4152.36

LogP -34.75

H-bond Donors 147.0

H-bond Acceptors 149.0

Rotatable Bonds 362.0

Heavy Atoms 740.0

Ring Count 13.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415215 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence