Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC99H153N25O30S4

DescriptionStandard

        IASKFICTPGCAKTGSFNSYCC
    

Molecular Weight2301.68 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)1.72

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0781

GRAVY Index0.43

Hydrophobic Moment 0.32

Boman Index0.20

Instability Index20.50

Aliphatic Index 44.55

Aromaticity 0.1364

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 882.14

LogP -11.50

H-bond Donors 35.0

H-bond Acceptors 36.0

Rotatable Bonds 71.0

Heavy Atoms 158.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250106 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configheterodetic tetracyclic lantipeptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other ModsLanthionine/methyllanthionine-containing lantipeptide; multiple thioether crosslinks

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus aureus SG 511 or E88

Activity8 μg/mL

MethodMIC

RECORD: Rec_0323531 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configheterodetic tetracyclic lantipeptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other ModsLanthionine/methyllanthionine-containing lantipeptide; multiple thioether crosslinks

Bio-Activity Profile

Function

Antimicrobial

TargetStreptococcus pyogenes ATCC 8668

Activity1 μg/mL

MethodMIC

RECORD: Rec_0332691 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

Tax ID2; 2

Structure & Mods

Configheterodetic tetracyclic lantipeptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other ModsLanthionine/methyllanthionine-containing lantipeptide; multiple thioether crosslinks

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0381750 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configheterodetic tetracyclic lantipeptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other ModsLanthionine/methyllanthionine-containing lantipeptide; multiple thioether crosslinks

Bio-Activity Profile

Function

Antimicrobial

TargetCorynebacterium xerosis ATCC 9755

Activity1 μg/mL

MethodMIC

RECORD: Rec_0391010 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configheterodetic tetracyclic lantipeptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other ModsLanthionine/methyllanthionine-containing lantipeptide; multiple thioether crosslinks

Bio-Activity Profile

Function

Antimicrobial

TargetStreptococcus pneumoniae ATCC 6302

Activity4 μg/mL

MethodMIC

FIRST PREV 1 2 3

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