MYP_085907
Basic Information
Unnamed
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-positive
Standard
22 amino acids
C99H153N25O30S4
Standard
Sequence
IASKFICTPGCAKTGSFNSYCC
Physicochemical Analysis
2301.68 Da
8.52
1.72
1.45
0.0781
0.43
0.32
0.20
20.50
44.55
0.1364
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
882.14
-11.50
35.0
36.0
71.0
158.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010822 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 45.5%, C 54.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive
RECORD: Rec_0018821 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
752-5). MOA: It sequesters lipid II and inhibits cell wall synthesis (for ref, see mutacin 1140). It seems that activity of the lantibiotic epidermin is regulated at the level of precursor peptide processing (Kies S,et al. 2003). Updated 9/2012; 7/2021GW
Bio-Activity Profile
Antimicrobial
P. acnes IF 31002
0.25 μg/mL
MIC
RECORD: Rec_0079467 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis TÃ ¼ 3298 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0084745 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
752-5). MOA: It sequesters lipid II and inhibits cell wall synthesis (for ref, see mutacin 1140). It seems that activity of the lantibiotic epidermin is regulated at the level of precursor peptide processing (Kies S,et al. 2003). Updated 9/2012; 7/2021GW
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa BC 19
128 μg/mL
MIC
RECORD: Rec_0109168 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
752-5). MOA: It sequesters lipid II and inhibits cell wall synthesis (for ref, see mutacin 1140). It seems that activity of the lantibiotic epidermin is regulated at the level of precursor peptide processing (Kies S,et al. 2003). Updated 9/2012; 7/2021GW
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 11775
128 μg/mL
MIC
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