Peptide Database

Peptide Namecycloviolacin O13

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC130H210N36O38S5

DescriptionStandard

        GLPGESCVWLPCLSAAIGCSCKSKVCYRN
    

Molecular Weight3045.60 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0590

GRAVY Index0.39

Hydrophobic Moment 0.26

Boman Index0.15

Instability Index50.66

Aliphatic Index 80.69

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1171.81

LogP -13.03

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 95.0

Heavy Atoms 209.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059498 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetTrichostrongylus colubriformis

Activity0.19

MethodIC50

RECORD: Rec_0407029 VERIFIED: YES