Peptide Database

Peptide Name2m (monomer Atrial natriuretic peptide- Fc )

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC169H269N59O53S4

DescriptionStandard

        SLRRSSCFGGRMDRIGAQSGLGCNSFRYGGSGGFCREGI
    

Molecular Weight4103.57 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)3.43

Net Charge (pH 7.4) 3.18

Charge Density (pH 7.0) 0.0880

GRAVY Index-0.38

Hydrophobic Moment 0.60

Boman Index-0.10

Instability Index64.29

Aliphatic Index 42.56

Aromaticity 0.1026

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1842.91

LogP -27.43

H-bond Donors 72.0

H-bond Acceptors 61.0

Rotatable Bonds 139.0

Heavy Atoms 285.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070492 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyNatriuretic peptide

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermFc region

Disulfide7-23

Other ModsComposite modified token region

Bio-Activity Profile

Function

Natriuretic Vasodilator

MethodELISA

Half-LifeFemale Wistar rats Plasma, in vivo; 14040 s