Peptide Database

Peptide NameDefensin; alpha; 41

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC450H718N124O141S8

DescriptionStandard

        MKTFVLLSALVLLAFQAQADPIHKTDEETNTEEQPGEEDQAVSISSGGQEGSALHEELSKKLICYCRIRGCKRRECVFGTCRNLFLTFVFCCS
    

Molecular Weight10377.78 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-3.37

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0362

GRAVY Index-0.12

Hydrophobic Moment 0.53

Boman Index0.00

Instability Index52.11

Aliphatic Index 80.75

Aromaticity 0.0753

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4289.65

LogP -45.21

H-bond Donors 155.0

H-bond Acceptors 148.0

Rotatable Bonds 352.0

Heavy Atoms 723.0

Ring Count 11.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290870 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic