Peptide Database

Peptide NameBeta-defensin 12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC359H592N108O96S9

DescriptionStandard

        MAEKRMLWFAAFLILLAVPGNAQGSKHICRTAGGQCRMGTCLSGEVRIGDCFSPVILCCKKYPVRKTTRELQRGA
    

Molecular Weight8245.79 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.1004

GRAVY Index0.07

Hydrophobic Moment 0.89

Boman Index0.02

Instability Index47.24

Aliphatic Index 82.00

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3281.62

LogP -31.95

H-bond Donors 123.0

H-bond Acceptors 114.0

Rotatable Bonds 276.0

Heavy Atoms 572.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363502 VERIFIED: NO

Provenance & Taxonomy

OrganismGavialis gangeticus [Animal]

FamilyDefensin

Tax ID94835

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal