MYP_085780
Peptide 1 (Hirudin mimetic peptide)
Hemostasis
▸
Anticoagulant activity
Standard
22 amino acids
C104H144N26O37
Standard
FPRPGGGGQGDFEPIPEDAYDE
2350.41 Da
4.05
-5.22
-5.44
-0.2374
-1.22
0.43
-0.04
71.89
22.27
0.1364
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
988.28
-10.19
30.0
32.0
69.0
167.0
7.0
22.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0055617
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Hirudin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
D-residue notation at positions 1; Mixed L/D stereochemistry with D-annotated positions 1
Bio-Activity Profile
Anticoagulant
0.0134±0.00046 μM
Ki
Sprague-Dawley (SD) rats plasma (Dose i/v injected), in vivo; 780 s
RECORD: Rec_0369482
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Hirudin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Stearic acid at Lys
Bio-Activity Profile
Anticoagulant
0.01524±0.00018 μM
Ki
Sprague-Dawley (SD) rats plasma (Dose i/v injected), in vivo; 12732 s