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MYP_085745
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Basic Information
B1AW-K
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C124H209N31O26S2
Standard
Sequence
FLPLLAGLAANFLPKIICKIARKC
Physicochemical Analysis
2614.31 Da
9.85
3.74
3.50
0.1557
1.12
0.82
0.32
12.30
146.67
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
898.09
-2.49
32.0
32.0
85.0
183.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
H838
5.15 μM
IC50
PMID37228702 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37228702/
RECORD: Rec_0053811 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
HMEC
26.45 μM
IC50
PaperDiscovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue.
RECORD: Rec_0109840 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
the peptide is toxic: hemolytic HC50 10.6 uM: highly hemolytic. Also HACaT cells
20.53 μM
IC50
PaperDiscovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue.
RECORD: Rec_0135786 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
Pseudomonas aeruginosa ATCC 9027
16 μM
MIC
PaperDiscovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue.
RECORD: Rec_0195321 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus but was unable to disrupt biofilms
>256 μM
MBEC
PaperDiscovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue.
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