Peptide Database

Peptide NameSLAY-screened peptide P1791

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H158N26O31S

DescriptionStandard

        SSPVLYTSFTIGLWTYRHCE
    

Molecular Weight2360.64 Da

Isoelectric Point (pI)6.48

Net Charge (pH 7.0)-0.46

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0228

GRAVY Index0.02

Hydrophobic Moment 0.28

Boman Index0.18

Instability Index51.98

Aliphatic Index 73.00

Aromaticity 0.2000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 912.94

LogP -7.45

H-bond Donors 35.0

H-bond Acceptors 33.0

Rotatable Bonds 69.0

Heavy Atoms 167.0

Ring Count 7.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0406696 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/