Peptide Database

Peptide NameLaterosporulin 10

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC265H407N75O75S7

DescriptionStandard

        ACVNQCPDAIDRFIVKDKGCHGVEKKYYKQVYVACMNGQHLYCRTEWGGPCQL
    

Molecular Weight6067.98 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.91

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0361

GRAVY Index-0.43

Hydrophobic Moment 0.71

Boman Index-0.04

Instability Index27.34

Aliphatic Index 62.45

Aromaticity 0.1132

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2432.18

LogP -22.16

H-bond Donors 88.0

H-bond Acceptors 86.0

Rotatable Bonds 198.0

Heavy Atoms 422.0

Ring Count 11.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384767 VERIFIED: YES

Provenance & Taxonomy

OrganismBrevibacillus sp. SKDU10 [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetRabbit erythrocytes ( at NA , Rabbit erythrocytes (<20% Hemolysis at 100 microM

Activity100 μM

MethodHemolysis

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