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MYP_085591
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Basic Information
Laterosporulin 10
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
53 amino acids
C265H407N75O75S7
Standard
Sequence
ACVNQCPDAIDRFIVKDKGCHGVEKKYYKQVYVACMNGQHLYCRTEWGGPCQL
Physicochemical Analysis
6067.98 Da
8.30
1.91
1.51
0.0361
-0.43
0.71
-0.04
27.34
62.45
0.1132
11460.00
11835.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2432.18
-22.16
88.0
86.0
198.0
422.0
11.0
58.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126842 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus sp [Bacterium]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus
4.0 μM
LD50
PaperLaterosporulin10: a novel defensin like Class IId bacteriocin from Brevibacillus sp. strain SKDU10 with inhibitory activity against microbial pathogens
RECORD: Rec_0155118 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus sp. SKDU10 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis MTCC 121
6 μM
MIC50
PMID27267959 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27267959/
RECORD: Rec_0182585 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus sp. SKDU10 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium smegmatis mc2-155
45 μM
MIC50
PMID27267959 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27267959/
RECORD: Rec_0185456 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus sp. SKDU10 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
16 μM
MIC
PMID27267959 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27267959/
RECORD: Rec_0203219 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus sp. SKDU10 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma H1299
7 μM
LC50
PMID27267959 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27267959/
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