Peptide Database

Peptide NameDermaseptin-A4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC138H233N41O41S

DescriptionStandard

        GMWSTIRNVGKSAAKAANLPAKAALGAISEAV
    

Molecular Weight3154.64 Da

Isoelectric Point (pI)10.29

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0862

GRAVY Index0.30

Hydrophobic Moment 0.73

Boman Index0.18

Instability Index23.64

Aliphatic Index 95.00

Aromaticity 0.0312

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1316.78

LogP -15.40

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 104.0

Heavy Atoms 221.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397566 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis annae [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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