Peptide Database

Peptide Nametheta-Defensin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC41H69N15O11S3

DescriptionStandard

        RCVCTRGFC
    

Molecular Weight1044.28 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)1.73

Net Charge (pH 7.4) 1.48

Charge Density (pH 7.0) 0.1923

GRAVY Index0.49

Hydrophobic Moment 0.29

Boman Index-0.17

Instability Index27.30

Aliphatic Index 32.22

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 440.15

LogP -5.50

H-bond Donors 20.0

H-bond Acceptors 16.0

Rotatable Bonds 32.0

Heavy Atoms 70.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416820 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio hamadryas [Animal]

FamilyAlpha-defensin; Defensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

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