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MYP_085491
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Basic Information
D-HALO-P8F-rev
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
26 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
AKKLXHALHXALLALXHLPHXLKKFF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0290389 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 5,10,16,21
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Enterococcus faecalis
11.2 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0302472 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 5,10,16,21
Bio-Activity Profile
Hemolytic
human red blood cells
>65.2 μM
HC50
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0387963 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 5,10,16,21
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Staphylococcus aureus
11.2 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0388181 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
D-HALO-P8F-rev
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Ornithine (O)
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum 3D7
10.3 μM
IC50; PLDH assay
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
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