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MYP_085412
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Basic Information
Phylloseptin-11
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
19 amino acids
C94H162N20O24
Standard
Sequence
FLSLLPSLVSGAVSLVKIL
Physicochemical Analysis
1956.41 Da
8.75
0.76
0.55
0.0400
1.86
0.43
0.59
29.43
194.74
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
685.27
-3.09
24.0
25.0
63.0
138.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018934 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Phylloseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperJ.M. Resende et al. / Peptides 29 (2008) 1633-1644. Solution NMR structures of the antimicrobial peptides phylloseptin-1, -2, and -3 and biological activity: The role of charges and hydrogen bonding interactions in stabilizing helix conformations Evidence URLhttps://www.uniprot.org/uniprotkb/Q0VZ40/entry
RECORD: Rec_0029275 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 63.2%, C 36.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0040328 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0167967 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
317381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperPhylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus.
RECORD: Rec_0255028 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
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