Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC458H703N125O124S14

DescriptionStandard

        MKPFNLSVAVIIMLAFLFIQEDPSGLMEGIRQYFDLSSRMSDISKQCSKFVLFTQAADNKRQKRHSGPCKFCCNCCGHMNFCGFCCEWRF
    

Molecular Weight10393.15 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)3.59

Net Charge (pH 7.4) 3.13

Charge Density (pH 7.0) 0.0399

GRAVY Index0.01

Hydrophobic Moment 0.67

Boman Index0.04

Instability Index38.17

Aliphatic Index 61.78

Aromaticity 0.1333

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4016.83

LogP -37.33

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 346.0

Heavy Atoms 721.0

Ring Count 18.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427157 VERIFIED: NO

Provenance & Taxonomy

OrganismHippocampus comes [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal