Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC756H1181N219O220S9

DescriptionStandard

        MVSKVQFNPRSRTDAIFVHCSATKPEMDIGVETIRMWHKQQGWLDVGYHFIIKRDGTVEEGRPVNVVGSHVKDWNSRSVGVCLVGGIDAKGKFEANFTPAQMNSLRNKLEELMSKYPNAELMAHHSVAAKACPSFDVKRWWTTNELVTSDRG
    

Molecular Weight17146.38 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0198

GRAVY Index-0.43

Hydrophobic Moment 0.57

Boman Index-0.04

Instability Index46.62

Aliphatic Index 70.46

Aromaticity 0.0855

Extinction Coeff. Reduced 30480.00

Extinction Coeff. Oxidized 30605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7075.04

LogP -71.65

H-bond Donors 249.0

H-bond Acceptors 238.0

Rotatable Bonds 568.0

Heavy Atoms 1204.0

Ring Count 30.0

Amide Bonds 163.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0339517 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage YZ1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic