Peptide Database

Peptide NameChromogranin-A

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length439 amino acids

Chemical FormulaC2071H3307N607O743S10

DescriptionStandard

        LPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELEQEEERLSKEWEDSKRWSKMDQLAKELTAEKRLEGQEEEEDNRDSSMKLSFRARAYGFRGPGPQLRRGWRPSSREDSLEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLQALRRG
    

Molecular Weight48917.69 Da

Isoelectric Point (pI)4.57

Net Charge (pH 7.0)-49.41

Net Charge (pH 7.4) -50.21

Charge Density (pH 7.0) -0.1126

GRAVY Index-1.24

Hydrophobic Moment 0.86

Boman Index-0.26

Instability Index78.98

Aliphatic Index 57.40

Aromaticity 0.0296

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28085.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245777 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyChromogranin/secretogranin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSer124 Phosphoserine; Tyr176 Phosphotyrosine; Ser185 Phosphoserine; Ser200 Phosphoserine; Ser252 Phosphoserine; Ser282 Phosphoserine; Gly301 Amidation; Ser304 Phosphoserine; Ser315 Phosphoserine; Ser380 Phosphoserine; Ser384 Phosphoserine; Arg438 Amidation

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor