Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC271H436N72O83S7

DescriptionStandard

        MDNEKYLQVVEDEELEQLVGGIGPGWVETLTKDCPWNMPVACVTIMGQRICKKCR
    

Molecular Weight6255.25 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-3.52

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0641

GRAVY Index-0.26

Hydrophobic Moment 0.49

Boman Index0.01

Instability Index48.95

Aliphatic Index 83.09

Aromaticity 0.0545

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2499.88

LogP -20.75

H-bond Donors 87.0

H-bond Acceptors 87.0

Rotatable Bonds 209.0

Heavy Atoms 433.0

Ring Count 8.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170354 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

RECORD: Rec_0186414 VERIFIED: NO