Peptide Database

Peptide NameHepcidin

Function Ontology

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Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC84H141N27O23S10

DescriptionStandard

        ICMFCCGCCHRSKCGMCCKT
    

Molecular Weight2217.84 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.1383

GRAVY Index0.67

Hydrophobic Moment 0.20

Boman Index0.05

Instability Index64.07

Aliphatic Index 19.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 799.30

LogP -10.03

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 73.0

Heavy Atoms 144.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099278 VERIFIED: YES

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyHepcidin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)