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MYP_085364
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Basic Information
Mitoparan [K8Orn,L14S], Mastoparan [A5,A8Orn,A10Aib,L14S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
INLKKLAXLXKKIS
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066738 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8,10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human astrocytoma U373-MG
30 μM
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0129565 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0139292 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8,10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
32 μg/mL
MIC
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0203142 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8,10
Bio-Activity Profile
Cytotoxic
Human embryonic kidney HEK293 cells
>32 μg/mL
Cytotoxicity
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0231946 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8,10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli
32 μg/mL
MIC
PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
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