Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC527H852N130O149S3

DescriptionStandard

        MVNNLSNKYVFMIAIIGLAFATLSSIAFISTLQISIGDTALLAGNSHLASTLGISAYAAKKAVDIIDAASAVVSIISLIGIVTGGAGAISYAIVATAKYMIRNYGKKYAAAW
    

Molecular Weight11489.38 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)3.58

Net Charge (pH 7.4) 3.29

Charge Density (pH 7.0) 0.0320

GRAVY Index0.94

Hydrophobic Moment 0.58

Boman Index0.40

Instability Index18.10

Aliphatic Index 128.30

Aromaticity 0.0893

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4411.87

LogP -39.21

H-bond Donors 157.0

H-bond Acceptors 157.0

Rotatable Bonds 378.0

Heavy Atoms 809.0

Ring Count 12.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076563 VERIFIED: NO

Provenance & Taxonomy

OrganismGracilibacillus boraciitolerans JCM 21714 [Bacterium]

FamilyBacteriocin

Tax ID1298598

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal