Peptide Database

Peptide NameSarafotoxin-A

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC105H160N28O34S5

DescriptionStandard

        CSCKDMTDKECLNFCHQDVIW
    

Molecular Weight2518.89 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.1042

GRAVY Index-0.34

Hydrophobic Moment 0.38

Boman Index-0.07

Instability Index67.27

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1017.67

LogP -9.69

H-bond Donors 38.0

H-bond Acceptors 38.0

Rotatable Bonds 83.0

Heavy Atoms 172.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213279 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]

FamilySarafotoxin

Tax ID1343144

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0316690 VERIFIED: NO