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MYP_085264
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Basic Information
Substance P
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Tachykinin peptide
Standard
11 amino acids
C60H92N16O13S
Standard
Sequence
KPRPGQFFGLM
Physicochemical Analysis
1277.54 Da
11.00
1.76
1.55
0.1599
-0.42
0.17
0.04
6.04
35.45
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
467.75
-2.54
15.0
16.0
39.0
90.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044641 VERIFIED: YES
Provenance & Taxonomy
Scyliorhinus canicula [Animal]
Substance P
7830
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Vasoactive Vasodilator
Mammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Substance P (Scyliorhinus canicula): PMID 7685693 PMID7685693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7685693/
RECORD: Rec_0059809 VERIFIED: NO
Provenance & Taxonomy
Scyliorhinus canicula [Animal]
Tachykinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0061225 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0066737 VERIFIED: YES
Provenance & Taxonomy
Scyliorhinus canicula [Animal]
Tachykinin
7830
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Tachykinin Neuropeptide Neuromodulator
PMID7685693 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7685693/