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MYP_085204
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Basic Information
N6-NH2-PEG24
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C107H165N39O26S2
Standard
Sequence
GFAWNVCVYRNGVRVCHRRAN
Physicochemical Analysis
2477.83 Da
10.72
3.83
3.54
0.1822
-0.31
0.80
-0.17
41.69
64.76
0.1429
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1086.89
-11.56
42.0
33.0
77.0
174.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0123936 VERIFIED: YES
Provenance & Taxonomy
Arenicola marina [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli CVCC195
8 μg/mL
MIC
PMID35549900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35549900/
RECORD: Rec_0125809 VERIFIED: YES
Provenance & Taxonomy
Arenicola marina [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
PEG12
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans CMCC98001
128 μg/mL
MIC
PMID35549900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35549900/
RECORD: Rec_0134003 VERIFIED: YES
Provenance & Taxonomy
Arenicola marina [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
PEG6
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. enteritidis CVCC3377
32 μg/mL
MIC
PMID35549900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35549900/
RECORD: Rec_0136750 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
7-16
APD analysis reveals that this sequence is similar (76.19%) to Arenicin-3 V=R: 19%, N: 14%, C=A: 10%. Chemical modification: one disulfide bond: C7-C16
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Escherichia coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7
0.5-1.0 μg/mL
MIC
PaperAntibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis.
RECORD: Rec_0138316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
7-16, 7-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
pullorum CVCC1789
0.5 μg/mL
MIC
PMID33348729 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33348729/
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