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MYP_085204
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Basic Information
N6-NH2-PEG24
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C107H165N39O26S2
Standard
Sequence
GFAWNVCVYRNGVRVCHRRAN
Physicochemical Analysis
2477.83 Da
10.72
3.83
3.54
0.1822
-0.31
0.80
-0.17
41.69
64.76
0.1429
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1086.89
-11.56
42.0
33.0
77.0
174.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018517 VERIFIED: YES
Provenance & Taxonomy
Arenicola marina [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
miniPEG
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli CVCC195
16 μg/mL
MIC
PMID35549900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35549900/
RECORD: Rec_0037348 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. pullorum CVCC1789
0.5 μg/mL
MIC
PMID28611436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28611436/
RECORD: Rec_0044424 VERIFIED: YES
Provenance & Taxonomy
Arenicola marina [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
PEG6
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa CICC21630
128 μg/mL
MIC
PMID35549900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35549900/
RECORD: Rec_0054157 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
7-16, 7-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
Staphylococcus aureus ATCC25923
1 μg/mL
MIC
PMID33348729 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33348729/
RECORD: Rec_0057770 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
7-16, 7-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive Hemolytic
The hemolysis of N6NH2 towards mouse erythrocytes
PMID33348729 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33348729/
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