Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length179 amino acids

Chemical FormulaC874H1382N260O242S4

DescriptionStandard

        MGRGAELLVPWAGIRTGVAVITVPQAAIDLAKRFEGFHRVAKNDPGRAHPYVCPAGYWTIGYGHLCDPKHPPITEAEAEAYLAQDLKAALAATLRYCPVLATEPEGRLAAIVDFTFNLGAGRLQTSTLRRRVNQRDWRGATQELRRWVYGGGRILPGLALRREAEVAHLDVDPLKSGAA
    

Molecular Weight19532.18 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)4.93

Net Charge (pH 7.4) 4.38

Charge Density (pH 7.0) 0.0276

GRAVY Index-0.17

Hydrophobic Moment 0.78

Boman Index0.02

Instability Index39.08

Aliphatic Index 91.17

Aromaticity 0.0782

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7968.76

LogP -81.00

H-bond Donors 283.0

H-bond Acceptors 256.0

Rotatable Bonds 624.0

Heavy Atoms 1380.0

Ring Count 35.0

Amide Bonds 186.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0257600 VERIFIED: YES

Provenance & Taxonomy

OrganismAcidithiobacillus phage AcaML1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic