Peptide Database

Peptide NameBeta-defensin 128

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC482H782N126O131S7

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNITGYCRKKCKVGERYEIGCLSGKLCCVNDEEEKKHVSFKKPHQHSGEKLSVQQDYIILPTITIFAV
    

Molecular Weight10662.59 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.22

Charge Density (pH 7.0) 0.0507

GRAVY Index0.00

Hydrophobic Moment 0.62

Boman Index0.03

Instability Index20.52

Aliphatic Index 103.66

Aromaticity 0.0860

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4160.99

LogP -30.67

H-bond Donors 149.0

H-bond Acceptors 146.0

Rotatable Bonds 369.0

Heavy Atoms 746.0

Ring Count 13.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290111 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence