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MYP_085075
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Basic Information
mCRAMP
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiviral
Standard
34 amino acids
C178H302N50O46
Standard
Sequence
GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ
Physicochemical Analysis
3878.61 Da
10.22
5.76
5.54
0.1694
-0.89
0.76
-0.19
17.94
88.82
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1603.45
-12.14
52.0
52.0
143.0
274.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275783 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperGallo R.L., Kim K.J., Bernfield M., Kozak C.A., Zanetti M., Merluzzi L., Gennaro R.;. "Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse."; J. Biol. Chem. 272:13088-13093. Evidence URLhttps://www.uniprot.org/uniprotkb/CRAM_MOUSE/entry
RECORD: Rec_0275813 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
Salmonella Typhimurium
3.12 μM
MIC
PaperProcessing site and gene structure for the murine antimicrobial peptide CRAMP
RECORD: Rec_0336365 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
Jurkat
16 μM
IC50
PaperProcessing site and gene structure for the murine antimicrobial peptide CRAMP
RECORD: Rec_0349523 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
Escherichia coli
3.12 μM
MIC
PaperProcessing site and gene structure for the murine antimicrobial peptide CRAMP
RECORD: Rec_0364391 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]; Mammalia [Animal]
10090; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID9237689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9237689/
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