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MYP_085075
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Basic Information
mCRAMP
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiviral
Standard
34 amino acids
C178H302N50O46
Standard
Sequence
GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ
Physicochemical Analysis
3878.61 Da
10.22
5.76
5.54
0.1694
-0.89
0.76
-0.19
17.94
88.82
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1603.45
-12.14
52.0
52.0
143.0
274.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013264 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
Staphylococcus aureus
3.12 μM
MIC
PaperProcessing site and gene structure for the murine antimicrobial peptide CRAMP
RECORD: Rec_0016330 VERIFIED: NO
Provenance & Taxonomy
Mus sp. [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 8202835 B2 Evidence URLhttps://patents.google.com/patent/US8202835B2/en PatentUS 8202835 B2
RECORD: Rec_0017021 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0069303 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
K562
28 μM
IC50
PaperProcessing site and gene structure for the murine antimicrobial peptide CRAMP
RECORD: Rec_0077756 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
A. xylosoxidans
32 μg/mL
MIC
PMID11557478 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557478/
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