Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length370 amino acids

Chemical FormulaC1859H2914N464O544S16

DescriptionStandard

        MKACCSLLLLSLVCVQLKANPGVKVRLTQKGLEYAKEVGLEILKQNMKKENFPDLTGYEKFGLGNVKYNISRIRIATVEFPSASMSLIPRTGIKLVIGNASLTADMNWNIRTWMFRDSGRSTVYISKVFVTAIFSTPLDNSGHTLISLTSCRTTSGDIDIKLNGKSGGKLNQGQNVQLFSCSNANRSVHVYIRILIIGKLFYSAVLMPIDDLAEIDYSLNSLPAVFRPYIELDLKGIVHPAGNYTGPPYVAAPFTIPDQTDSMLYLAFSEYFFQTSSFAYYTAGAFNRTIAEETYSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATETPLISLQPDSFTLEIQGSMEVFAVLPDSTNQSLFTMNTVS
    

Molecular Weight40980.84 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0020

GRAVY Index0.11

Hydrophobic Moment 0.66

Boman Index0.15

Instability Index31.53

Aliphatic Index 95.65

Aromaticity 0.1081

Extinction Coeff. Reduced 37820.00

Extinction Coeff. Oxidized 38070.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031281 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence